The pressure rise results in the generation of ultrasonic waves called photoacoustic (PA) waves. When excited by an optical pulse, biomolecules experience an increase in temperature due to optical absorption, and hence a pressure rise due to thermo-elastic expansion. Photoacoustic imaging (PAI) is a hybrid biomedical imaging technique that detects ultrasonic waves induced by the excitation of short optical pulses 1, 2, 3, 4, 5, 6, 7. Our DNN-assisted raster scanning framework can further potentially be applied to other raster scanning-based biomedical imaging tools, such as optical coherence tomography, ultrasound microscopy, and confocal microscopy. The proposed method doubles the imaging speed compared to that of conventional methods by aligning nonlinear mismatched cross-sectional B-scan photoacoustic images during bidirectional raster scanning. Here, we demonstrate a scanning framework based on a deep neural network (DNN) to correct misaligned PAM images acquired via bidirectional raster scanning. Therefore, only one unidirectionally acquired image is typically used consequently, the imaging speed is reduced by half. However, when using high-speed water-immersible scanners, the two consecutively acquired bidirectional PAM images are misaligned with each other because of unstable performance, which causes a non-uniform time interval between scanning points. Here you will find options to view and activate subscriptions, manage institutional settings and access options, access usage statistics, and more.Simultaneous point-by-point raster scanning of optical and acoustic beams has been widely adapted to high-speed photoacoustic microscopy (PAM) using a water-immersible microelectromechanical system or galvanometer scanner. If you believe you should have access to that content, please contact your librarian.įor librarians and administrators, your personal account also provides access to institutional account management. The institutional subscription may not cover the content that you are trying to access. Oxford Academic is home to a wide variety of products. View the institutional accounts that are providing access.View your signed in personal account and access account management features.Some societies use Oxford Academic personal accounts to provide access to their members.Ĭlick the account icon in the top right to: See below.Ī personal account can be used to get email alerts, save searches, purchase content, and activate subscriptions. Some societies use Oxford Academic personal accounts to provide access to their members.

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